Sign in or Register   Sign in or Register
  |  

Mouse Anti-DHFR2 Recombinant Antibody (1E2) (CBMAB-D0826-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dihydrofolate Reductase 2 (DHFR2). The antibody can be used for immunoassay techniques, such as WB, ICC, IF.
See all DHFR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Dog
Clone
1E2
Antibody Isotype
IgG2b
Application
WB, ICC, IF

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 4-185 of human DHFRL1(NP_789785) produced in E.coli
Specificity
Human, Mouse, Dog
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dihydrofolate Reductase 2
Introduction
DHFR2 (Dihydrofolate Reductase 2) is a protein coding gene. Among its related pathways are One carbon pool by folate and Metabolism. And a paralog is DHFR.
Entrez Gene ID
Human200895
Mouse111208
UniProt ID
HumanQ86XF0
Alternative Names
Dihydrofolate Reductase 2; Dihydrofolate Reductase, Mitochondrial; Dihydrofolate Reductase-Like Protein 1; Dihydrofolate Reductase Pseudogene 4; Dihydrofolate Reductase Like 1; EC 1.5.1.3;
Function
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
Biological Process
Dihydrofolate metabolic process Source: GO_Central
Folic acid metabolic process Source: GO_Central
Glycine biosynthetic process Source: InterPro
One-carbon metabolic process Source: UniProtKB-KW
Tetrahydrofolate biosynthetic process Source: GO_Central
Tetrahydrofolate metabolic process Source: UniProtKB
Thymidine biosynthetic process Source: UniProtKB
Cellular Location
Mitochondrion; Mitochondrion matrix; Mitochondrion inner membrane
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-DHFR2 Recombinant Antibody (1E2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare