Rabbit Anti-DUSP9 Recombinant Antibody (EG1008) (V2LY-0425-LY1099)

Name: Rabbit Anti-DUSP9 Recombinant Antibody (EG1008)
SKU: V2LY-0425-LY1099
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Rabbit

Specificity

Human

Clone

EG1008

Antibody Isotype

IgG

Application

IF, WB, IHC-P

Basic Information

Immunogen

Synthetic peptide corresponding to residues near the C-terminus of human DUSP9 protein.

Host Species

Rabbit

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:1,000
IF(ICC)	1:800-1:3,000
IHC-P	1:50-1:200

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

BSA & Glycerol & HEPES

Preservative

Sodium Azide

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Dual Specificity Phosphatase 9

Entrez Gene ID

1852

UniProt ID

Q99956

Research Area

Inactivates MAP kinases. Has a specificity for the ERK family.

Biological Process

Activation of MAPK activity Source: Reactome
Inactivation of MAPK activity Source: GO_Central
JNK cascade Source: ProtInc
MAPK cascade Source: Reactome
Negative regulation of ERK1 and ERK2 cascade Source: GO_Central
Peptidyl-threonine dephosphorylation Source: GO_Central
Peptidyl-tyrosine dephosphorylation Source: GO_Central
Positive regulation of apoptotic process Source: GO_Central
Protein dephosphorylation Source: GO_Central
Regulation of heart growth Source: GO_Central

Cellular Location

Cytoplasm

More Infomation

References

Khoubai, F. Z., & Grosset, C. F. (2021). DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases. International Journal of Molecular Sciences, 22(21), 11538.

Chen, K., Gorgen, A., Ding, A., Du, L., Jiang, K., Ding, Y., ... & Ghanekar, A. (2021). Dual‐Specificity Phosphatase 9 Regulates Cellular Proliferation and Predicts Recurrence after Surgery in Hepatocellular Carcinoma. Hepatology communications, 5(7), 1310-1328.

Jiang, L., Ren, L., Guo, X., Zhao, J., Zhang, H., Chen, S., ... & Xia, J. (2021). Dual-specificity phosphatase 9 protects against cardiac hypertrophy by targeting ASK1. International Journal of Biological Sciences, 17(9), 2193.

Acharya, S., Dutta, S., Mudrale, S. P., & Bose, K. (2020). Dual specificity phosphatase 9: A novel binding partner cum substrate of proapoptotic serine protease HtrA2. Biochemical and Biophysical Research Communications, 533(3), 607-612.

Ye, P., Xiang, M., Liao, H., Liu, J., Luo, H., Wang, Y., ... & Xia, J. (2019). Dual‐specificity phosphatase 9 Protects against nonalcoholic fatty liver disease in mice through ASK1 suppression. Hepatology, 69(1), 76-93.

Wei, Q., Pu, X., Zhang, L., Xu, Y., Duan, M., & Wang, Y. (2019). Expression of dual-specificity phosphatase 9 in placenta and its relationship with gestational diabetes mellitus. Journal of Diabetes Research, 2019.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Antibody Pairs

DUSP9 Matched Antibody Pair (354)

Related Products

Mouse Anti-DUSP9 Recombinant Antibody (CBFYM-1080)

DUSP9 Matched Antibody Pair (354)

Mouse Anti-DUSP9 Recombinant Antibody (2E3)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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