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Mouse Anti-E. coli ACNB Recombinant Antibody (CBMW-H1234) (CBMAB-V208-1408-FY)

This product is mouse antibody that recognizes E. coli ACNB. The antibody CBMW-H1234 can be used for immunoassay techniques such as: ELISA, WB.
See all E. coli ACNB antibodies

Summary

Host Animal
Mouse
Specificity
E. coli
Clone
CBMW-H1234
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Specificity
E. coli
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Escherichia Coli Acnb
Introduction
The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch.
Entrez Gene ID
UniProt ID
Alternative Names
E. coli ACNB; Escherichia coli ACNB
Research Area
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript.
Biological Process
Glyoxylate cycle
Propionate catabolic process, 2-methylcitrate cycle
Regulation of translation
Tricarboxylic acid cycle
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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