Mouse Anti-E. coli ACNB Recombinant Antibody (CBMW-H1234) (CBMAB-V208-1408-FY)

Name: Mouse Anti-E. coli ACNB Recombinant Antibody (CBMW-H1234)
SKU: CBMAB-V208-1408-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBMW-H1234

Application

ELISA, WB

Specificity

E. coli

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Escherichia Coli Acnb

Introduction

The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch.

Entrez Gene ID

944864

UniProt ID

P36683

Alternative Names

E. coli ACNB; Escherichia coli ACNB

Research Area

Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript.

Biological Process

Glyoxylate cycle
Propionate catabolic process, 2-methylcitrate cycle
Regulation of translation
Tricarboxylic acid cycle

Cellular Location

Cytosol

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rabbit Anti-E. coli AcnB Recombinant Antibody (CBMW-H1234) (CAT#: V2LY-0425-LY1180)

Related Products

Mouse Anti-E. coli AcnB Recombinant Antibody (CBMW-H1395) (CAT#: V2LY-0425-LY1176)

Rabbit Anti-E. coli AcnB Recombinant Antibody (CBMW-H1234) (CAT#: V2LY-0425-LY1180)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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