E. coli ACNB

The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch.
Full Name
Escherichia Coli Acnb
Research Area
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript.
Biological Process
Glyoxylate cycle
Propionate catabolic process, 2-methylcitrate cycle
Regulation of translation
Tricarboxylic acid cycle
Cellular Location
Cytosol
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Anti-E. coli ACNB antibodies

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Rabbit Anti-E. coli AcnB Recombinant Antibody (CBMW-H1234) (V2LY-0425-LY1180)

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Target: E. coli AcnB
Host: Rabbit
Antibody Isotype: IgG
Specificity: E. coli
Clone: CBMW-H1234
Application*: E
Datasheet SDS

Mouse Anti-E. coli AcnB Recombinant Antibody (CBMW-H1395) (V2LY-0425-LY1176)

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Target: E. coli AcnB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: E. coli
Clone: CBMW-H1395
Application*: E
Datasheet SDS

Mouse Anti-E. coli ACNB Recombinant Antibody (CBMW-H1234) (CBMAB-V208-1408-FY)

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Target: E. coli ACNB
Host: Mouse
Antibody Isotype: IgG
Specificity: E. coli
Clone: CBMW-H1234
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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