Mouse Anti-E. coli AcnB Recombinant Antibody (CBMW-H1395) (V2LY-0425-LY1176)

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Datasheet
SDS
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Basic Information

Host Animal
Mouse
Clone
CBMW-H1395
Application
ELISA
Immunogen
Recombinant Escherichia coli acnB.
Host Species
Mouse
Specificity
E. coli
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Escherichia Coli Acnb
Research Area
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript.
Biological Process
Glyoxylate cycle
Propionate catabolic process, 2-methylcitrate cycle
Regulation of translation
Tricarboxylic acid cycle
Cellular Location
Cytosol
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-E. coli AcnB Recombinant Antibody (CBMW-H1234) (CAT#: V2LY-0425-LY1180)

Mouse Anti-E. coli ACNB Recombinant Antibody (CBMW-H1234) (CAT#: CBMAB-V208-1408-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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