Mouse Anti-EAF1 Recombinant Antibody (CBFYE-0011) (CBMAB-E0022-FY)

This product is mouse antibody that recognizes EAF1. The antibody CBFYE-0011 can be used for immunoassay techniques such as: ELISA, WB.
See all EAF1 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYE-0011

Antibody Isotype

IgG2a, κ

Application

ELISA, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

ELL associated factor 1

Introduction

EAF1 (ELL Associated Factor 1) is a Protein Coding gene. Diseases associated with EAF1 include Eaf. Among its related pathways are Gene Expression and Formation of HIV elongation complex in the absence of HIV Tat. An important paralog of this gene is EAF2.

Entrez Gene ID

85403

UniProt ID

Q96JC9

Alternative Names

ELL Associated Factor 1

Research Area

Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.

Biological Process

Regulation of transcription elongation from RNA polymerase II promoter Source: ARUK-UCL

Cellular Location

Nucleus speckle; Cajal body

References

Basu, S., Nandy, A., Barad, M. K., Pal, S., & Biswas, D. (2022). Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions. Molecular and Cellular Biology, e00151-22.

Liu, R., Chen, C., Li, Y., Huang, Q., & Xue, Y. (2020). ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 1863(5), 194508.

Pascal, L. E., Su, F., Wang, D., Ai, J., Song, Q., Wang, Y., ... & Wang, Z. (2019). Conditional deletion of eaf1 induces murine prostatic intraepithelial neoplasia in mice. Neoplasia, 21(8), 752-764.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-EAF1 Recombinant Antibody (1G2)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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