Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586) (CBMAB-V208-1595-FY)

Name: Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586)
SKU: CBMAB-V208-1595-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBMW-H1586

Application

ELISA, IF

Specificity

EBV

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Epstein-Barr Virus Nuclear Antigen 1

Introduction

The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known viruses in the herpes family, and is one of the most common viruses in humans.

Alternative Names

EBV EBNA-1; Epstein–Barr virus EBNA-1

Research Area

Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.

Biological Process

Positive regulation of transcription, DNA-templated Source: InterPro
Regulation of DNA replication Source: InterPro
Suppression by virus of host adaptive immune response Source: UniProtKB-KW
Suppression by virus of host antigen processing and presentation Source: UniProtKB-KW
Suppression by virus of host NF-kappaB transcription factor activity Source: UniProtKB-KW
Viral latency Source: UniProtKB-KW

Cellular Location

Host nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586) (CAT#: V2LY-0425-LY1314)

Related Products

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1355) (CAT#: CBMAB-V208-1715-FY)

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1356) (CAT#: V2LY-0425-LY1313)

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586) (CAT#: V2LY-0425-LY1314)

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1355) (CAT#: V2LY-0425-LY1312)

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1356) (CAT#: CBMAB-V208-1716-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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