EBV EBNA-1

The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known viruses in the herpes family, and is one of the most common viruses in humans.
Full Name
Epstein-Barr Virus Nuclear Antigen 1
Research Area
Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.
Biological Process
Positive regulation of transcription, DNA-templated Source: InterPro
Regulation of DNA replication Source: InterPro
Suppression by virus of host adaptive immune response Source: UniProtKB-KW
Suppression by virus of host antigen processing and presentation Source: UniProtKB-KW
Suppression by virus of host NF-kappaB transcription factor activity Source: UniProtKB-KW
Viral latency Source: UniProtKB-KW
Cellular Location
Host nucleus
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Anti-EBV EBNA-1 antibodies

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Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1355) (CBMAB-V208-1715-FY)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG1
Specificity: EBV
Clone: CBMW-H1355
Application*: E, IC, IP, WB
Datasheet SDS

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586) (V2LY-0425-LY1314)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Epstein-Barr Virus
Clone: CBMW-H1586
Application*: E
Datasheet SDS

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1356) (V2LY-0425-LY1313)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Epstein-Barr Virus
Clone: CBMW-H1356
Application*: E, WB
Datasheet SDS

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1355) (V2LY-0425-LY1312)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Epstein-Barr Virus
Clone: CBMW-H1355
Application*: IP, WB
Datasheet SDS

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1586) (CBMAB-V208-1595-FY)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: EBV
Clone: CBMW-H1586
Application*: E, IF
Datasheet SDS

Mouse Anti-EBV EBNA-1 Recombinant Antibody (CBMW-H1356) (CBMAB-V208-1716-FY)

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Target: EBV EBNA-1
Host: Mouse
Antibody Isotype: IgG1
Specificity: EBV
Clone: CBMW-H1356
Application*: IH, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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