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Mouse Anti-EFNA2 Recombinant Antibody (CBFYE-0488) (V2LY-0425-LY1506)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0488
Antibody Isotype
IgG2b
Application
WB, IHC, IF, FC

Basic Information

Immunogen
Full length human recombinant protein of human EFNA2 produced in HEK293T cell.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:2,000
IF(ICC)1:100
IHC1:150
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & Glycerol & PBS
Preservative
Sodium Azide
Concentration
1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Ephrin A2
Entrez Gene ID
1943
UniProt ID
O43921
Research Area
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
Biological Process
Axon guidance Source: GO_Central
Bone remodeling Source: UniProtKB
Cell-cell signaling Source: ProtInc
Ephrin receptor signaling pathway Source: UniProtKB
Olfactory bulb development Source: Ensembl
Osteoclast differentiation Source: UniProtKB
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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