EFNA2

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]
Full Name
Ephrin A2
Research Area
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
Biological Process
Axon guidance Source: GO_Central
Bone remodeling Source: UniProtKB
Cell-cell signaling Source: ProtInc
Ephrin receptor signaling pathway Source: UniProtKB
Olfactory bulb development Source: Ensembl
Osteoclast differentiation Source: UniProtKB
Cellular Location
Cell membrane
View more

Anti-EFNA2 antibodies

+ Filters
Loading...

Rat Recombinant EFNA2 protein, hFc Tag (V2LY-0526-LY9358)

Go to compareCompare
Target: EFNA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-183
Tag: hFc Tag
Datasheet SDS

Mouse Recombinant EFNA2 protein, His Tag (V2LY-0526-LY8259)

Go to compareCompare
Target: EFNA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-184
Tag: His Tag
Datasheet SDS

Mouse Recombinant EFNA2 protein (V2LY-0526-LY8258)

Go to compareCompare
Target: EFNA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-184
Datasheet SDS

Mouse Anti-EFNA2 Recombinant Antibody (CBFYE-0488) (V2LY-0425-LY1506)

Go to compareCompare
Target: EFNA2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-0488
Application*: WB, IH, IF, F
Datasheet SDS

Mouse Anti-EFNA2 Recombinant Antibody (EG1038) (CBMAB-EN1223-LY)

Go to compareCompare
Target: EFNA2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: EG1038
Application*: WB, IF
Datasheet SDS

Rat Anti-EFNA2 Recombinant Antibody (CBFYE-0486) (CBMAB-E0835-FY)

Go to compareCompare
Target: EFNA2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYE-0486
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.