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Mouse Anti-EFNA4 Recombinant Antibody (CBFYE-0496) (CBMAB-E0849-FY)

This product is mouse antibody that recognizes EFNA4. The antibody CBFYE-0496 can be used for immunoassay techniques such as: WB.
See all EFNA4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0496
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to human Ephrin-A4
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ephrin A4
Introduction
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified.
Entrez Gene ID
UniProt ID
Alternative Names
Ephrin A4; Ephrin-A4; LERK-4; EPLG4; LERK4; Eph-Related Receptor Tyrosine Kinase Ligand 4; EPH-Related Receptor Tyrosine Kinase Ligand 4; Ligand Of Eph-Related Kinase 4; EFL4
Research Area
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Biological Process
Axon guidance Source: GO_Central
Cell-cell signaling Source: ProtInc
Ephrin receptor signaling pathway Source: GO_Central
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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