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Mouse Anti-EID2 Recombinant Antibody (CBFYE-0631) (CBMAB-E1037-FY)

This product is mouse antibody that recognizes EID2. The antibody CBFYE-0631 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all EID2 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBFYE-0631
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
EP300 Interacting Inhibitor Of Differentiation 2
Introduction
EID2 (EP300 Interacting Inhibitor Of Differentiation 2) is a Protein Coding gene. Among its related pathways are TGF-beta Signaling Pathway (WikiPathways). Gene Ontology (GO) annotations related to this gene include SMAD binding. An important paralog of this gene is EID2B.
Entrez Gene ID
Human163126
Mouse386655
Rat685691
UniProt ID
HumanQ8N6I1
MouseQ6X7S9
RatD4ACB5
Alternative Names
EP300 Interacting Inhibitor Of Differentiation 2; CREBBP/EP300 Inhibitor 2; EID-1-Like Inhibitor Of Differentiation 2; CREBBP/EP300 Inhibitory Protein 2; EID-2; CRI2; EP300-Interacting Inhibitor Of Differentiation 2; E1A Like Inhibitor Of Differentiation 2
Research Area
Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Biological Process
Cell differentiation Source: UniProtKB-KW
Muscle organ development Source: UniProtKB-KW
Negative regulation of transcription, DNA-templated Source: HGNC-UCL
Negative regulation of transcription by RNA polymerase II Source: InterPro
Negative regulation of transforming growth factor beta receptor signaling pathway Source: HGNC-UCL
Regulation of cell population proliferation Source: HGNC-UCL
Regulation of transforming growth factor beta receptor signaling pathway Source: HGNC-UCL
SMAD protein complex assembly Source: HGNC-UCL
Transforming growth factor beta receptor complex assembly Source: HGNC-UCL
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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