Mouse Anti-EIF3H Recombinant Antibody (3B12) (CBMAB-A2533-LY)
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                            Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632).
The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process Source: FlyBase
Regulation of translational initiation Source: UniProtKB
Translational initiation Source: UniProtKB
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                                            Please try the standard protocols which include: protocols, troubleshooting and guide.
                                            
                                            Enzyme-linked Immunosorbent Assay (ELISA)
                                            
                                            
                                            Flow Cytometry
                                            
                                            
                                            Immunofluorescence (IF)
                                            
                                            
                                            Immunohistochemistry (IHC)
                                            
                                            
                                            Immunoprecipitation (IP)
                                            
                                            
                                            Western Blot (WB)
                                            
                                            
                                            Enzyme Linked Immunospot (ELISpot)
                                            
                                            
                                            Proteogenomic
                                            
                                            
                                            Other Protocols
                                            
                                            
                                        
Alternative Versions
                                                
                                                Mouse Anti-EIF3H Recombinant Antibody (3B12) (CAT#: V2LY-0425-LY1697)
                                            
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Mouse Anti-EIF3H Recombinant Antibody (3C6) (CAT#: V2LY-0425-LY1698)
Mouse Anti-EIF3H Recombinant Antibody (3B12) (CAT#: V2LY-0425-LY1697)
Mouse Anti-EIF3H Recombinant Antibody (CBFYE-0182) (CAT#: V2LY-0425-LY1695)
Mouse Anti-EIF3H Recombinant Antibody (CBFYE-0182) (CAT#: CBMAB-E0425-FY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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