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Rat Anti-ENPEP Recombinant Antibody (CBWJC-2117) (V2LY-0825-LY278)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rat
Clone
CBWJC-2117
Application
IP, FC
Immunogen
Mouse ENPEP.
Host Species
Rat
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, gelatin
Preservative
Sodium azide
Concentration
0.1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Glutamyl Aminopeptidase
Entrez Gene ID
13809
UniProt ID
P16406
Research Area
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Biological Process
Angiogenesis Source: UniProtKB
Angiotensin maturation Source: UniProtKB
Cell-cell signaling Source: UniProtKB
Cell migration Source: MGI
Cell population proliferation Source: MGI
Glomerulus development Source: UniProtKB
Peptide catabolic process Source: GO_Central
Proteolysis Source: GO_Central
Regulation of blood pressure Source: GO_Central
Regulation of systemic arterial blood pressure by renin-angiotensin Source: UniProtKB
Signal transduction Source: GO_Central
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-18
Helical: 19-39
Extracellular: 40-957

Wang, A., Chu, H., Jin, Z., Gong, Z., Jia, Q., & Zhu, B. (2022). ENPEP as a potential predictor of immune checkpoint inhibitor efficacy. Cancer Medicine, 11(3), 880-887.

Aung, M., Konoshita, T., Moodley, J., Naicker, T., Connolly, C., Khaliq, O. P., & Gathiram, P. (2021). Aminopeptidase A (ENPEP) gene polymorphisms and preeclampsia: Descriptive analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 258, 70-74.

Berillo, O., Ouerd, S., Idris-Khodja, N., Rehman, A., Richer, C., Sinnett, D., ... & Schiffrin, E. L. (2021). Chromosome 2 fragment substitutions in Dahl salt-sensitive rats and RNA sequencing identified Enpep and Hs2st1 as vascular inflammatory modulators. Hypertension, 77(1), 178-189.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Rat Anti-ENPEP Recombinant Antibody (CBFYE-0113) (CAT#: V2LY-0825-LY274)

Rat Anti-ENPEP Recombinant Antibody (63) (CAT#: CBMAB-A4390-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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