Mouse Anti-F2RL3 Recombinant Antibody (CBXF-0162) (V2LY-0825-LY1107)

Name: Mouse Anti-F2RL3 Recombinant Antibody (CBXF-0162)
SKU: V2LY-0825-LY1107
Rating: 5 (1 reviews)

See all F2RL3 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-0162

Application

ELISA

Immunogen

Human F2RL3.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

F2R Like Thrombin Or Trypsin Receptor 3

Entrez Gene ID

9002

UniProt ID

Q96RI0

Research Area

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

Biological Process

Blood coagulation Source: ProtInc
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: ProtInc
Platelet activation Source: Reactome
Platelet dense granule organization Source: BHF-UCL
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: GO_Central
Positive regulation of release of sequestered calcium ion into cytosol Source: BHF-UCL
Positive regulation of Rho protein signal transduction Source: GO_Central
Response to wounding Source: ProtInc
Signal transduction Source: ProtInc

Cellular Location

Cell membrane

Topology

Extracellular: 48-82
Helical: 83-103
Cytoplasmic: 104-108
Helical: 109-129
Extracellular: 130-151
Helical: 152-172
Cytoplasmic: 173-192
Helical: 193-213
Extracellular: 214-247
Helical: 248-268
Cytoplasmic: 269-283
Helical: 284-304
Extracellular: 305-319
Helical: 320-343
Cytoplasmic: 344-385

PTM

A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., van den Bosch, M. T., ... & Timpson, N. J. (2022). Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function. Circulation research, 130(3), 384-400.

Cao, D., Qu, Y., Zhang, X., Xu, F., Zhou, S., Zhang, G., ... & Zhao, J. (2018). High expression of F2RL3 correlates with aggressive features and poor survival in clear cell renal cell carcinoma. Journal of Cancer, 9(18), 3400.

Alhamdow, A., Lindh, C., Hagberg, J., Graff, P., Westberg, H., Krais, A. M., ... & Broberg, K. (2018). DNA methylation of the cancer-related genes F2RL3 and AHRR is associated with occupational exposure to polycyclic aromatic hydrocarbons. Carcinogenesis, 39(7), 869-878.

Gao, B. F., Shen, Z. C., Bian, W. S., Wu, S. X., Kang, Z. X., & Gao, Y. (2018). Correlation of hypertension and F2RL3 gene methylation with Prognosis of coronary heart disease. Journal of Biological Regulators and Homeostatic Agents, 32(6), 1539-1544.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-F2RL3 Recombinant Antibody (CBXF-0162)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human F2RL3 ELISA Kit (CAT#: V2LY-0626-LY5727)

Mouse Anti-F2RL3 Recombinant Antibody (CBXF-2110) (CAT#: V2LY-0825-LY1108)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry