Mouse Anti-FDX1 Recombinant Antibody (CBXF-0486) (V2LY-0925-LY1162)

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Basic Information

Host Animal
Mouse
Clone
CBXF-0486
Application
ELISA, WB
Immunogen
FDX1 (aa 85-183) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
ferredoxin 1
Entrez Gene ID
UniProt ID
Research Area
Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783).

Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783).

Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783).

Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
Biological Process
Cellular response to cAMP Source: Ensembl
Cellular response to forskolin Source: Ensembl
Cholesterol metabolic process Source: UniProtKB
Hormone biosynthetic process Source: UniProtKB
Steroid biosynthetic process Source: UniProtKB-KW
Cellular Location
Mitochondrion matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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