Rabbit Anti-FDX1 Recombinant Antibody (CBXF-1201) (V2LY-0925-LY1161)

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Basic Information

Host Animal
Rabbit
Clone
CBXF-1201
Application
IHC, WB, IF
Immunogen
Synthetic peptide within Human FDX1 (aa 51-100).
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1:500-1:1,000
IF(ICC)1:50
IHC1:200-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
TBS & BSA & Glycerol
Preservative
Sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
ferredoxin 1
Entrez Gene ID
Human2230
Mouse14148
Rat29189
UniProt ID
HumanP10109
MouseP46656
RatP24483
Research Area
Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783).

Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783).

Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783).

Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
Biological Process
Cellular response to cAMP Source: Ensembl
Cellular response to forskolin Source: Ensembl
Cholesterol metabolic process Source: UniProtKB
Hormone biosynthetic process Source: UniProtKB
Steroid biosynthetic process Source: UniProtKB-KW
Cellular Location
Mitochondrion matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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