Rat Anti-FKBP1B Recombinant Antibody (CBXF-3046) (V2LY-0925-LY2052)

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Basic Information

Host Animal
Rat
Clone
CBXF-3046
Application
WB, IHC
Immunogen
Recombinant human FKBP12.6 (Gly2-Glu108).
Host Species
Rat
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1 μg/ml
IHC5-20 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS & Trehalose
Preservative
None
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
FK506 binding protein 1B, 12.6 kDa
Entrez Gene ID
UniProt ID
Function
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Biological Process
de novo' protein folding Source: BHF-UCL
Calcium-mediated signaling using intracellular calcium source Source: BHF-UCL
Cell communication by electrical coupling involved in cardiac conduction Source: BHF-UCL
Chaperone-mediated protein folding Source: GO_Central
Insulin secretion Source: Ensembl
Negative regulation of heart rate Source: BHF-UCL
Negative regulation of insulin secretion involved in cellular response to glucose stimulus Source: Ensembl
Negative regulation of phosphoprotein phosphatase activity Source: BHF-UCL
Negative regulation of release of sequestered calcium ion into cytosol Source: BHF-UCL
Negative regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Neuronal action potential propagation Source: Ensembl
Positive regulation of axon regeneration Source: Ensembl
Positive regulation of sequestering of calcium ion Source: BHF-UCL
Protein maturation by protein folding Source: BHF-UCL
Protein peptidyl-prolyl isomerization Source: BHF-UCL
Protein refolding Source: BHF-UCL
Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Source: BHF-UCL
Regulation of cytosolic calcium ion concentration Source: BHF-UCL
Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: BHF-UCL
Regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Release of sequestered calcium ion into cytosol Source: Ensembl
Response to glucose Source: Ensembl
Response to hydrogen peroxide Source: Ensembl
Response to redox state Source: BHF-UCL
Response to vitamin E Source: Ensembl
Smooth muscle contraction Source: Ensembl
T cell proliferation Source: Ensembl
Cellular Location
Cytoplasm; Sarcoplasmic reticulum
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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