Rabbit Anti-FNTB Recombinant Antibody (CBXF-1204) (CBMAB-F0935-CQ)

This product is a rabbit antibody that recognizes FNTB. The antibody CBXF-1204 can be used for immunoassay techniques such as: WB, ICC.
See all FNTB antibodies

Datasheet

Summary

Host Animal

Rabbit

Specificity

Rat, Human

Clone

CBXF-1204

Antibody Isotype

IgG

Application

WB, ICC

Basic Information

Specificity

Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

farnesyltransferase, CAAX box, beta

Entrez Gene ID

Human	2342
Rat	64511

UniProt ID

Human	P49356
Rat	Q02293

Alternative Names

Farnesyltransferase, CAAX Box, Beta; Ras Proteins Prenyltransferase Subunit Beta; CAAX Farnesyltransferase Subunit Beta; EC 2.5.1.58; FTase-Beta; Protein Farnesyltransferase Subunit Beta; FPTB;

Function

Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.

Biological Process

Protein farnesylation Source: UniProtKB
Protein prenylation Source: GO_Central

Cellular Location

Microtubule associated complex; Cytosol; Protein farnesyltransferase complex

References

Bachmann, H. S., Jung, D., Link, T., Arnold, A., Kantelhardt, E., Thomssen, C., ... & Kuhlmann, J. D. (2022). FNTB promoter polymorphisms are independent predictors of survival in patients with triple negative breast cancer. Cancers, 14(3), 468.

Ding, J., Chen, Y. X., Chen, Y., Mou, Y., Sun, X. T., Dai, D. P., ... & Guo, X. (2020). Overexpression of FNTB and the activation of Ras induce hypertrophy and promote apoptosis and autophagic cell death in cardiomyocytes. Journal of Cellular and Molecular Medicine, 24(16), 8998-9011.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-FNTB Recombinant Antibody (CBXF-0803)

Mouse Anti-FNTB Recombinant Antibody (3A9)

Mouse Anti-FNTB Recombinant Antibody (CBXF-3112)

Rabbit Anti-FNTB Recombinant Antibody (CBXF-1205)

Rabbit Anti-FNTB Recombinant Antibody (EG1218)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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