Mouse Anti-FRMD5 Recombinant Antibody (CBXF-1798) (V2LY-1225-LY101)

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBXF-1798
Application
WB, IP, IF, ELISA
Immunogen
Amino acids 134-173 mapping within an internal region of human FRMD5.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
ApplicationNote
ELISA1:100-1:1,000
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, gelatin
Preservative
Sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
FERM Domain Containing 5
Entrez Gene ID
UniProt ID
Function
May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675).

May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).
Biological Process
Actomyosin structure organization Source: GO_Central
Negative regulation of cell motility Source: UniProtKB
Positive regulation of cell adhesion Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Cellular Location
Membrane; Adherens junction
Topology
Helical: 504-524
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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