FRMD5

FRMD5 (FERM Domain Containing 5) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cytoskeletal protein binding. An important paralog of this gene is FRMD3.
Full Name
FERM Domain Containing 5
Function
May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675).

May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).
Biological Process
Actomyosin structure organization Source: GO_Central
Negative regulation of cell motility Source: UniProtKB
Positive regulation of cell adhesion Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Cellular Location
Membrane; Adherens junction
Topology
Helical: 504-524
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Anti-FRMD5 antibodies

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Mouse Anti-FRMD5 Recombinant Antibody (CBXF-1798) (CBMAB-F3333-CQ)

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Target: FRMD5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1798
Application*: WB, IP, IF, E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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