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Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720) (CBMAB-C4984WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3720
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FYN Binding Protein 2
Introduction
FYB2 (FYN Binding Protein 2) is a Protein Coding gene.
Entrez Gene ID
199920
UniProt ID
Q5VWT5
Alternative Names
FYN Binding Protein 2; Activation-Dependent, Raft-Recruited ADAP-Like Phosphoprotein; C1orf168; ARAP; Chromosome 1 Open Reading Frame 168; Uncharacterized Protein C1orf168; FYN-Binding Protein 2; RP4-758N20.2;
Function
Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation (PubMed:27335501).
Biological Process
Cell adhesion mediated by integrin Source: UniProtKB
Integrin-mediated signaling pathway Source: GO_Central
Protein localization to plasma membrane Source: GO_Central
T cell receptor signaling pathway Source: UniProtKB
Cellular Location
Membrane raft. Recruited to membrane rafts and immunological synapse after TCR stimulation.
PTM
Phosphorylation is required for its function in T-cell activation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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