Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720) (V2LY-1225-LY360)

Name: Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720)
SKU: V2LY-1225-LY360
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBWJC-3720

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 281-506 mapping within an internal region of human FYB2.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

FYN Binding Protein 2

Entrez Gene ID

199920

UniProt ID

Q5VWT5

Function

Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation (PubMed:27335501).

Biological Process

Cell adhesion mediated by integrin Source: UniProtKB
Integrin-mediated signaling pathway Source: GO_Central
Protein localization to plasma membrane Source: GO_Central
T cell receptor signaling pathway Source: UniProtKB

Cellular Location

Membrane raft. Recruited to membrane rafts and immunological synapse after TCR stimulation.

PTM

Phosphorylation is required for its function in T-cell activation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720) (CAT#: CBMAB-C4984WJ)

Related Products

Mouse Anti-FYB2 Recombinant Antibody (CBXC-1791) (CAT#: V2LY-1225-LY359)

Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720) (CAT#: CBMAB-C4984WJ)

Mouse Anti-FYB2 Recombinant Antibody (CBXC-1791) (CAT#: CBMAB-C5432-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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