FYB2

FYB2 (FYN Binding Protein 2) is a Protein Coding gene.

Full Name

FYN Binding Protein 2

Function

Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation (PubMed:27335501).

Biological Process

Cell adhesion mediated by integrin Source: UniProtKB
Integrin-mediated signaling pathway Source: GO_Central
Protein localization to plasma membrane Source: GO_Central
T cell receptor signaling pathway Source: UniProtKB

Cellular Location

Membrane raft. Recruited to membrane rafts and immunological synapse after TCR stimulation.

PTM

Phosphorylation is required for its function in T-cell activation.

Anti-FYB2 antibodies

Mouse Anti-FYB2 Recombinant Antibody (CBXC-1791) (CBMAB-C5432-CQ)

Datasheet

SDS

Target: FYB2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXC-1791

Application*: WB, IP, IF, E

Mouse Anti-FYB2 Recombinant Antibody (CBWJC-3720) (CBMAB-C4984WJ)

Datasheet

SDS

Target: FYB2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBWJC-3720

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)