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Rabbit Anti-G3BP2 Recombinant Antibody (EG1262) (CBMAB-EN1525-LY)

The product is antibody recognizes G3BP2. The antibody EG1262 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:10000.
See all G3BP2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1262
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from C-terminal of human G3BP2.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G3BP2
Entrez Gene ID
Human9908
Mouse23881
Rat305240
UniProt ID
HumanQ9UN86
MouseP97379
RatQ6AY21
Function
Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
Biological Process
Cytoplasmic sequestering of NF-kappaB Source: UniProtKB
Innate immune response Source: UniProtKB-KW
mRNA transport Source: UniProtKB-KW
Positive regulation of stress granule assembly Source: UniProtKB
Protein homooligomerization Source: UniProtKB
Ras protein signal transduction Source: UniProtKB
Stress granule assembly Source: InterPro
Cellular Location
Cytoplasm; Stress granule
PTM
Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine.
(Microbial infection) Cleaved by foot-and-mouth disease virus leader protease; this cleavage suppresses the formation of cytoplasmic stress granules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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