Human G3BP2 ELISA Kit (V2LY-0626-LY5769)

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Tested Data
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Basic Information

Sensitivity
0.01 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
54.1 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
G3BP2
Function
Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
Biological Process
Cytoplasmic sequestering of NF-kappaB Source: UniProtKB
Innate immune response Source: UniProtKB-KW
mRNA transport Source: UniProtKB-KW
Positive regulation of stress granule assembly Source: UniProtKB
Protein homooligomerization Source: UniProtKB
Ras protein signal transduction Source: UniProtKB
Stress granule assembly Source: InterPro
Cellular Location
Cytoplasm; Stress granule
PTM
Arg-457 and Arg-468 are dimethylated, probably to asymmetric dimethylarginine.
(Microbial infection) Cleaved by foot-and-mouth disease virus leader protease; this cleavage suppresses the formation of cytoplasmic stress granules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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