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Mouse Anti-GABRE Recombinant Antibody (1G11) (CBMAB-1549-CN)

This product is a mouse antibody that recognizes GABRE of human. The antibody 1G11 can be used for immunoassay techniques such as: WB, ELISA.
See all GABRE antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G11
Antibody Isotype
IgG2a
Application
WB, ELISA

Basic Information

Immunogen
GABRE (AAH59376.1, aa. 1-100) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Ascites
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
Localized in aa. 1-100

Target

Full Name
Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit
Introduction
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Entrez Gene ID
2564
UniProt ID
P78334
Alternative Names
gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon; GABA(A) receptor, epsilon; gamma-aminobutyric acid (GABA) A receptor, epsilon
Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Biological Process
Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: GO_Central
Gamma-aminobutyric acid signaling pathway Source: GO_Central
Ion transmembrane transport Source: GO_Central
Negative regulation of chloride transport Source: GO_Central
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Regulation of postsynaptic membrane potential Source: GO_Central
Signal transduction Source: GO_Central
Synaptic transmission, GABAergic Source: GO_Central
Cellular Location
Postsynaptic cell membrane; Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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