Rabbit Anti-GABRE Recombinant Antibody (S413-67) (CBMAB-1550-CN)

Name: Rabbit Anti-GABRE Recombinant Antibody (S413-67)
SKU: CBMAB-1550-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Rabbit

Clone

S413-67

Application

WB, ICC, IF, IHC

Immunogen

Fusion protein aa. 27-253 (Extracellular N-terminus) of human GABA A Receptor Epsilon

Specificity

Human, Rat

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% Glycerol

Preservative

0.1% Sodium azide

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

Localized in aa. 27-253

More Infomation

Target

Full Name

Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit

Introduction

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Entrez Gene ID

Human	2564
Rat	65191

UniProt ID

Human	P78334
Rat	Q9ES14

Alternative Names

gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon; GABA(A) receptor, epsilon; gamma-aminobutyric acid (GABA) A receptor, epsilon

Function

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Biological Process

Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: GO_Central
Gamma-aminobutyric acid signaling pathway Source: GO_Central
Ion transmembrane transport Source: GO_Central
Negative regulation of chloride transport Source: GO_Central
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Regulation of postsynaptic membrane potential Source: GO_Central
Signal transduction Source: GO_Central
Synaptic transmission, GABAergic Source: GO_Central

Cellular Location

Postsynaptic cell membrane; Cell membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-GABRE Recombinant Antibody (S413-67) (CAT#: CBMAB-AP2448LY)

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Mouse Anti-GABRE Recombinant Antibody (CBLG1-465) (CAT#: CBMAB-G1697-LY)

Mouse Anti-GABRE Recombinant Antibody (1G11) (CAT#: CBMAB-1549-CN)

Mouse Anti-GABRE Recombinant Antibody (CBLG1-464) (CAT#: CBMAB-G1696-LY)

Mouse Anti-GABRE Recombinant Antibody (S413-67) (CAT#: CBMAB-AP2448LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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