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GABRE

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008]
Full Name
Gamma-Aminobutyric Acid Type A Receptor Epsilon Subunit
Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Biological Process
Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: GO_Central
Gamma-aminobutyric acid signaling pathway Source: GO_Central
Ion transmembrane transport Source: GO_Central
Negative regulation of chloride transport Source: GO_Central
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Regulation of postsynaptic membrane potential Source: GO_Central
Signal transduction Source: GO_Central
Synaptic transmission, GABAergic Source: GO_Central
Cellular Location
Postsynaptic cell membrane; Cell membrane
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Anti-GABRE antibodies

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Mouse Anti-GABRE Recombinant Antibody (CBLG1-465) (CBMAB-G1697-LY)

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Target: GABRE
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat, Mouse
Clone: CBLG1-465
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-GABRE Recombinant Antibody (CBLG1-464) (CBMAB-G1696-LY)

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Target: GABRE
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Human, Rat
Clone: CBLG1-464
Application*: IC, IH, WB
Datasheet SDS

Mouse Anti-GABRE Recombinant Antibody (S413-67) (CBMAB-AP2448LY)

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Target: GABRE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Rat
Clone: S413-67
Application*: ICC/IF, IHC, WB
Datasheet SDS

Mouse Anti-GABRE (AA 27-253) Recombinant Antibody (CBFYH-2865) (CBMAB-H0290-FY)

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Target: GABRE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Rat
Clone: CBFYH-2865
Application*: WB, IH, IF
Datasheet SDS

Rabbit Anti-GABRE Recombinant Antibody (S413-67) (CBMAB-1550-CN)

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Target: GABRE
Host: Rabbit
Antibody Isotype: IgG2a
Specificity: Human, Rat
Clone: S413-67
Application*: WB, IC, IF, IH
Datasheet SDS

Mouse Anti-GABRE Recombinant Antibody (1G11) (CBMAB-1549-CN)

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Target: GABRE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1G11
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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