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Mouse Anti-GAD2 Recombinant Antibody (114-4E8) (CBMAB-G1730-LY)

This product is antibody recognizes GAD2. The antibody 114-4E8 immunoassay techniques such as: WB.
Host Animal
Mouse
Application
WB
Antibody Isotype
IgG2a
Specificity
Human
Cross Reactivity
Human
Clone
114-4E8
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Alternative Name
Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain; 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65;
Entrez Gene ID
UniProt ID