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Mouse Anti-GALNT6 (AA 523-623) Recombinant Antibody (CBFYH-0234) (CBMAB-H1104-FY)

This product is mouse antibody that recognizes GALNT6. The antibody CBFYH-0234 can be used for immunoassay techniques such as: ELISA, WB.
See all GALNT6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0234
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant from GALNT6 with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 523-623

Target

Full Name
Polypeptide N-Acetylgalactosaminyltransferase 6
Introduction
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
Entrez Gene ID
11226
UniProt ID
Q8NCL4
Alternative Names
Polypeptide N-Acetylgalactosaminyltransferase 6; Polypeptide GalNAc Transferase 6; UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 6 (GalNAc-T6); UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 6; Protein-UDP Acetylgalactosaminyltransferase 6; Pp-GaNTase 6
Function
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides.
Biological Process
O-glycan processing Source: Reactome
Protein O-linked glycosylation Source: ProtInc
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-8
Helical: 9-28
Lumenal: 29-622
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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