Sign in or Register   Sign in or Register
  |  

Mouse Anti-GBP2 Recombinant Antibody (CBFYH-0269) (CBMAB-H1143-FY)

This product is mouse antibody that recognizes GBP2. The antibody CBFYH-0269 can be used for immunoassay techniques such as: WB, IHC.
See all GBP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0269
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
Full-length protein expressed in 293T cell transfected with human GBP2 expression vector
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, PH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
0.44 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Guanylate Binding Protein 2
Introduction
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.
Entrez Gene ID
2634
UniProt ID
P32456
Alternative Names
Guanylate Binding Protein 2; Guanylate Binding Protein 2, Interferon-Inducible; Interferon-Induced Guanylate-Binding Protein 2; Guanine Nucleotide-Binding Protein 2; GTP-Binding Protein 2; EC 3.6.5.-; HuGBP-2; GBP-2
Function
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832).

Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).
Biological Process
Cellular response to interferon-gamma Source: UniProtKB
Cellular response to interleukin-1 Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Defense response to Gram-positive bacterium Source: GO_Central
Defense response to protozoan Source: GO_Central
Immune response Source: ProtInc
Protein localization to nucleus Source: UniProtKB
Cellular Location
Cytoplasm; Golgi apparatus membrane; Perinuclear region; Membrane. GBP2-GBP5 dimers localize to the Golgi apparatus.
PTM
Isoprenylation is required for proper subcellular location.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GBP2 Recombinant Antibody (CBFYH-0269)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare