Mouse Anti-GBP2 Recombinant Antibody (CBFYH-0271) (V2LY-1225-LY831)

Name: Mouse Anti-GBP2 Recombinant Antibody (CBFYH-0271)
SKU: V2LY-1225-LY831
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYH-0271

Application

ELISA, WB, IP

Immunogen

Full-length recombinant GBP2.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Guanylate Binding Protein 2

Entrez Gene ID

2634

UniProt ID

P32456

Function

Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832).

Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).

Biological Process

Cellular response to interferon-gamma Source: UniProtKB
Cellular response to interleukin-1 Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Defense response to Gram-positive bacterium Source: GO_Central
Defense response to protozoan Source: GO_Central
Immune response Source: ProtInc
Protein localization to nucleus Source: UniProtKB

Cellular Location

Cytoplasm; Golgi apparatus membrane; Perinuclear region; Membrane. GBP2-GBP5 dimers localize to the Golgi apparatus.

PTM

Isoprenylation is required for proper subcellular location.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GBP2 Recombinant Antibody (CBFYH-0271) (CAT#: CBMAB-H1145-FY)

Antibody Pairs

GBP2 Matched Antibody Pair (469) (CAT#: APMAB-469LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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