Mouse Anti-GCKR Recombinant Antibody (CBLG1-2678) (V2LY-1225-LY908)
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Basic Information
| Application | Note |
| WB | 1:2,000 |
| IF(ICC) | 1:100 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10456334).
The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (PubMed:23621087, PubMed:23733961).
Carbohydrate metabolic process Source: UniProtKB-KW
Glucose homeostasis Source: GO_Central
Negative regulation of glucokinase activity Source: UniProtKB
Protein import into nucleus Source: BHF-UCL
Response to fructose Source: BHF-UCL
Triglyceride homeostasis Source: BHF-UCL
Urate metabolic process Source: BHF-UCL
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Mouse Anti-GCKR Recombinant Antibody (CBLG1-2678) (CAT#: CBMAB-G2624-LY)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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