Recombinant full length protein
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Diseases associated with GCLM include Myocardial Infarction and Ancylostomiasis. Among its related pathways are Glutathione metabolism and Metabolism.
Glutamate-Cysteine Ligase Modifier Subunit; Glutamate-Cysteine Ligase; Modifier Subunit; Gamma-Glutamylcysteine Synthetase Regulatory Subunit; Gamma-ECS Regulatory Subunit; GCS Light Chain; GLCLR; Glutamate-Cysteine Ligase (Gamma-Glutamylcysteine Synthetase); Regulatory (30.8kD); Glutamate-Cysteine Ligase Modifier Subunit Delta2 Alternative Splicing; Glutamate-Cysteine Ligase Regulatory Protein; Glutamate--Cysteine Ligase Modifier Subunit; Gamma-Glutamylcysteine Synthetase; GSC Light Chain