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Mouse Anti-GJC1 Recombinant Antibody (CBLG1-1208) (CBMAB-G3584-LY)

This product is antibody recognizes GJC1. The antibody CBLG1-1208 immunoassay techniques such as: ICC, IHC-P, WB.
See all GJC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-1208
Antibody Isotype
IgG1
Application
ICC, IHC-P, WB

Basic Information

Immunogen
Synthetic peptide corresponding to aa354-367 of human connexin 45. (H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu- Cys-OH) (KLH)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
gap junction protein gamma 1
Introduction
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Gap Junction Protein Gamma 1; Gap Junction Protein; Gamma 1; 45kDa; Gap Junction Alpha-7 Protein; Connexin-45; CX45; GJA7;
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
atrial cardiac muscle cell action potential Source: BHF-UCL
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-22
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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