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Mouse Anti-GJC1 Recombinant Antibody (CBYY-C3070) (CBMAB-C4513-YY)

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Basic Information

Host Animal
Mouse
Clone
CBYY-C3070
Application
WB, IF
Immunogen
The peptide sequence used for the immunogen was H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu-Cys-OH conjugated to KLH, corresponding to amino acids 354-377 of human connexin 45
Specificity
Human, Rat, Rabbit
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A/G purified
Buffer
1 mg/mL
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
gap junction protein gamma 1
Entrez Gene ID
Human10052
Rabbit100009380
Rat266706
UniProt ID
HumanP36383
RabbitG1TFR1
RatA4GG66
Alternative Names
CO2; ARMD14
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
atrial cardiac muscle cell action potential Source: BHF-UCL
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-22
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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