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GJC1

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
Full Name
gap junction protein gamma 1
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
atrial cardiac muscle cell action potential Source: BHF-UCL
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-22
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396

Anti-GJC1 antibodies

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Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 5C7G1
Application*: C, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0368
Application*: IC, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q265
Application*: WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1208
Application*: IC, P, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1210
Application*: IC, IH, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Rabbit, Human
Clone: CBYY-C3069
Application*: WB, IC, F
Target: GJC1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1321
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Rabbit, Human
Clone: 5B9.2
Application*: WB, C, F
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Rabbit
Clone: CBYY-C3070
Application*: WB, IF
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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