GJC1
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
Full Name
gap junction protein gamma 1
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
atrial cardiac muscle cell action potential Source: BHF-UCL
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-22
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396
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Anti-GJC1 antibodies
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CompareTarget: GJC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C3070
Application*: WB, IP, IF, E
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 5C7G1
Application*: C, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Rabbit, Human
Clone: 5B9.2
Application*: WB, C, F
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1210
Application*: IC, IH, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1208
Application*: IC, P, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 265
Application*: WB, IF, IH
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0368
Application*: IC, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Rabbit, Dog
Clone: EG1321
Application*: IF, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Mouse, Rabbit
Clone: CBFYH-0368
Application*: IF, WB
Target: GJC1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1321
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBYY-C3069
Application*: WB, IH, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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