GJC1

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
Full Name
gap junction protein gamma 1
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
atrial cardiac muscle cell action potential Source: BHF-UCL
AV node cell to bundle of His cell communication by electrical coupling Source: BHF-UCL
Cardiac muscle tissue development Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Cell development Source: Ensembl
Chemical synaptic transmission Source: Ensembl
Gap junction assembly Source: BHF-UCL
Muscle contraction Source: ProtInc
SA node cell to atrial cardiac muscle cell communication by electrical coupling Source: BHF-UCL
Vasculogenesis Source: Ensembl
Visual perception Source: Ensembl
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-22
Helical: 23-45
Extracellular: 46-75
Helical: 76-95
Cytoplasmic: 96-175
Helical: 176-198
Extracellular: 199-228
Helical: 229-248
Cytoplasmic: 249-396
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Anti-GJC1 antibodies

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Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Rabbit
Clone: CBYY-C3070
Application*: WB, IF
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 5C7G1
Application*: C, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Rabbit, Human
Clone: 5B9.2
Application*: WB, C, F
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1210
Application*: IC, IH, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1208
Application*: IC, P, WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q265
Application*: WB
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0368
Application*: IC, WB
Target: GJC1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1321
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Target: GJC1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Rabbit, Human
Clone: CBYY-C3069
Application*: WB, IC, F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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