Sign in or Register   Sign in or Register
  |  

Mouse Anti-GK Recombinant Antibody (CBLG1-1223) (CBMAB-G3603-LY)

This product is antibody recognizes GK. The antibody CBLG1-1223 immunoassay techniques such as: WB.
See all GK antibodies

Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBLG1-1223
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Glucokinase
Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% NaN3
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glycerol kinase
Introduction
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Entrez Gene ID
79223
UniProt ID
Q63060
Alternative Names
ASTP; Gyk
Function
Key enzyme in the regulation of glycerol uptake and metabolism.
Biological Process
Glycerol-3-phosphate biosynthetic process Source: BHF-UCL
Glycerol catabolic process Source: UniProtKB-UniPathway
Glycerol metabolic process Source: BHF-UCL
Phosphorylation Source: GO_Central
Triglyceride biosynthetic process Source: Reactome
Triglyceride metabolic process Source: BHF-UCL
Cellular Location
Cytoplasm; Mitochondrion outer membrane. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
Involvement in disease
Glycerol kinase deficiency (GKD):
A metabolic disorder manifesting as 3 clinically distinct forms: infantile, juvenile, and adult. The infantile form is the most severe and is associated with severe developmental delay and adrenal insufficiency. Patients with the adult form have no symptoms and are often detected fortuitously. GKD results in hyperglycerolemia, a condition characterized by the accumulation of glycerol in the blood and urine.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GK Recombinant Antibody (CBLG1-1223)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare