Mouse Anti-GLRA2 Recombinant Antibody (CBLG1-3184) (CBMAB-G3857-LY)

Name: Mouse Anti-GLRA2 Recombinant Antibody (CBLG1-3184)
SKU: CBMAB-G3857-LY
Rating: 5 (1 reviews)

See all GLRA2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLG1-3184

Application

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Glycine Receptor Alpha 2

Introduction

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Entrez Gene ID

2742

UniProt ID

P23416

Alternative Names

Glycine Receptor Alpha 2; Glycine Receptor; Alpha-2 Polypeptide; Glycine Receptor Alpha 2 Subunit; Glycine Receptor Subunit Alpha-2; GLR;

Function

Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488).

Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677).

Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

Plays a role in cellular responses to ethanol (PubMed:23895467).

Biological Process

Cellular response to amino acid stimulus Source: UniProtKB
Cellular response to ethanol Source: UniProtKB
Cellular response to zinc ion Source: UniProtKB
Chemical synaptic transmission Source: GO_Central
Chloride transmembrane transport Source: UniProtKB
Ion transmembrane transport Source: UniProtKB
Nervous system process Source: GO_Central
Neuropeptide signaling pathway Source: UniProtKB
Regulation of membrane potential Source: GO_Central
Response to amino acid Source: GO_Central
Signal transduction Source: GO_Central
Synaptic transmission, glycinergic Source: GO_Central

Cellular Location

Postsynaptic cell membrane; Cell membrane; Synapse; Cell projection

Topology

Extracellular: 28-256
Helical: 257-278
Cytoplasmic: 279-283
Helical: 284-304
Extracellular: 305-315
Helical: 316-336
Cytoplasmic: 337-420
Helical: 421-441
Extracellular: 442-452

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-GLRA2 Recombinant Antibody (CBLG1-3184)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry