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Mouse Anti-GPLD1 Recombinant Antibody (38A1) (CBMAB-G4600-LY)

This product is antibody recognizes GPLD1. The antibody 38A1 immunoassay techniques such as: ELISA (EIA), WB.
See all GPLD1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
38A1
Antibody Isotype
IgG1, κ
Application
ELISA (EIA), WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol, 0.01% BSA
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glycosylphosphatidylinositol Specific Phospholipase D1
Introduction
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]
Entrez Gene ID
2822
UniProt ID
P80108
Alternative Names
Glycosylphosphatidylinositol Specific Phospholipase D1; Glycoprotein Phospholipase D; GPI-Specific Phospholipase D; EC 3.1.4.50; PI-G PLD; GPI-PLD; PIGPLD1;
Function
This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.
Biological Process
Cell migration involved in sprouting angiogenesis Source: UniProtKB
Cellular response to calcium ion Source: UniProtKB
Cellular response to cholesterol Source: UniProtKB
Cellular response to drug Source: UniProtKB
Cellular response to insulin stimulus Source: UniProtKB
Cellular response to pH Source: UniProtKB
Cellular response to triglyceride Source: UniProtKB
Chondrocyte differentiation Source: UniProtKB
Complement receptor mediated signaling pathway Source: UniProtKB
C-terminal protein lipidation Source: Reactome
GPI anchor release Source: UniProtKB
Hematopoietic stem cell migration Source: UniProtKB
Hematopoietic stem cell migration to bone marrow Source: UniProtKB
Insulin receptor signaling pathway Source: UniProtKB
Negative regulation of cell population proliferation Source: UniProtKB
Negative regulation of triglyceride catabolic process Source: UniProtKB
Ossification Source: UniProtKB
Phosphatidylcholine metabolic process Source: UniProtKB
Positive regulation of alkaline phosphatase activity Source: UniProtKB
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of endothelial cell migration Source: UniProtKB
Positive regulation of glucose metabolic process Source: UniProtKB
Positive regulation of high-density lipoprotein particle clearance Source: UniProtKB
Positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: UniProtKB
Positive regulation of membrane protein ectodomain proteolysis Source: UniProtKB
Positive regulation of secretion Source: UniProtKB
Positive regulation of triglyceride biosynthetic process Source: UniProtKB
Regulation of cellular response to insulin stimulus Source: UniProtKB
Response to glucose Source: UniProtKB
Transepithelial transport Source: UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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