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Mouse Anti-HELZ Recombinant Antibody (1C11) (CBMAB-A3821-LY)

The product is antibody recognizes HELZ. The antibody 1C11 immunoassay techniques such as: WB, ELISA.
See all HELZ antibodies
Published Data
Fig.1 Immunoblot analysis of HEK293 cells cultured under normoxic or hypoxic conditions for the indicated time periods.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
1C11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
HELZ (NP_055692, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
helicase with zinc finger
Introduction
HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM
Entrez Gene ID
9931
UniProt ID
P42694
Alternative Names
DHRC; DKFZp586G1924; DRHC; HUMORF5; KIAA0054; MGC163454
Function
May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo.
Biological Process
Post-transcriptional gene silencing by RNA Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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