Mouse Anti-HELZ (AA 1-101) Recombinant Antibody (CBFYH-0923) (CBMAB-H1856-FY)

Name: Mouse Anti-HELZ (AA 1-101) Recombinant Antibody (CBFYH-0923)
SKU: CBMAB-H1856-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0923

Application

ELISA, WB

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-101

More Infomation

Target

Full Name

helicase with zinc finger

Introduction

HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).

Entrez Gene ID

9931

UniProt ID

P42694

Alternative Names

Helicase With Zinc Finger; Down-Regulated In Human Cancers Protein; DRHC; Probable Helicase With Zinc Finger Domain; Helicase With Zinc Finger Domain; Down-Regulated In Human Cancers

Function

May act as a helicase that plays a role in RNA metabolism in multiple tissues and organs within the developing embryo.

Biological Process

Post-transcriptional gene silencing by RNA Source: GO_Central

Cellular Location

Nucleus

Hanet, A., Räsch, F., Weber, R., Ruscica, V., Fauser, M., Raisch, T., ... & Wohlbold, L. (2019). HELZ directly interacts with CCR4–NOT and causes decay of bound mRNAs. Life science alliance, 2(5).

Hanet, A. J. (2019). Roles of the putative RNA helicase HELZ in mRNA regulation (Doctoral dissertation, Universität Tübingen).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-HELZ (AA 1-100) Recombinant Antibody (CBFYH-0924) (CAT#: CBMAB-H1857-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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