Mouse Anti-ID4 Antibody (1A6) (CBMAB-0523-YC)

Name: Mouse Anti-ID4 Antibody (1A6)
SKU: CBMAB-0523-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1A6

Application

IP, MA

Immunogen

Recombinant protein

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

inhibitor of DNA binding 4, HLH protein

Introduction

ID4 (inhibitor of DNA binding 4, dominant negative helix-loop-helix protein) a member of the inhibitor of DNA binding (ID) protein family. ID4, lacking DNA binding ability, regulates gene expression through binding to and inhibiting basic helix-loop-helix transcription factors. Besides, ID4 has been implicated in the regulation of diverse cellular processes that play a role in development and tumorigenesis.

Entrez Gene ID

3400

UniProt ID

P47928

Alternative Names

IDB4; bHLHb27

Function

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity).

Biological Process

Cell differentiation Source: GO_Central
Cellular protein localization Source: Ensembl
Central nervous system myelination Source: Ensembl
Cerebral cortex neuron differentiation Source: Ensembl
Circadian regulation of gene expression Source: GO_Central
Fat cell differentiation Source: Ensembl
G1/S transition of mitotic cell cycle Source: Ensembl
Hippocampus development Source: Ensembl
Negative regulation of astrocyte differentiation Source: Ensembl
Negative regulation of fat cell differentiation Source: Ensembl
Negative regulation of neuron differentiation Source: Ensembl
Negative regulation of oligodendrocyte differentiation Source: Ensembl
Negative regulation of transcription, DNA-templated Source: GDB
Negative regulation of transcription by RNA polymerase II Source: ARUK-UCL
Neuroblast proliferation Source: Ensembl
Osteoblast differentiation Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Prostate gland epithelium morphogenesis Source: Ensembl
Prostate gland stromal morphogenesis Source: Ensembl
Seminal vesicle morphogenesis Source: Ensembl

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-ID4 Antibody (1A1) (CAT#: CBMAB-0521-YC)

Rabbit Anti-ID4 Recombinant Antibody (EG1604) (CAT#: CBMAB-EN1918-LY)

Mouse Anti-ID4 Antibody (3C6) (CAT#: CBMAB-0527-YC)

Mouse Anti-ID4 Antibody (1A10) (CAT#: CBMAB-0522-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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