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Rabbit Anti-ID4 Recombinant Antibody (EG1604) (CBMAB-EN1918-LY)

The product is antibody recognizes ID4. The antibody EG1604 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:20000.
See all ID4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1604
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human ID4.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
inhibitor of DNA binding 4, HLH protein
Introduction
This gene encodes a member of the inhibitor of DNA binding (ID) protein family. The encoded protein lacks DNA binding ability, and instead regulates gene expression through binding to and inhibiting basic helix-loop-helix transcription factors. This protein has been implicated in the regulation of diverse cellular processes that play a role in development and tumorigenesis.
Entrez Gene ID
Human3400
Mouse15904
Rat291023
UniProt ID
HumanP47928
MouseP41139
RatE9PU21
Alternative Names
IDB4; bHLHb27
Function
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity).
Biological Process
Cell differentiation Source: GO_Central
Cellular protein localization Source: Ensembl
Central nervous system myelination Source: Ensembl
Cerebral cortex neuron differentiation Source: Ensembl
Circadian regulation of gene expression Source: GO_Central
Fat cell differentiation Source: Ensembl
G1/S transition of mitotic cell cycle Source: Ensembl
Hippocampus development Source: Ensembl
Negative regulation of astrocyte differentiation Source: Ensembl
Negative regulation of fat cell differentiation Source: Ensembl
Negative regulation of neuron differentiation Source: Ensembl
Negative regulation of oligodendrocyte differentiation Source: Ensembl
Negative regulation of transcription, DNA-templated Source: GDB
Negative regulation of transcription by RNA polymerase II Source: ARUK-UCL
Neuroblast proliferation Source: Ensembl
Osteoblast differentiation Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Prostate gland epithelium morphogenesis Source: Ensembl
Prostate gland stromal morphogenesis Source: Ensembl
Seminal vesicle morphogenesis Source: Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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