Mouse Anti-IFT57 Recombinant Antibody (CBYY-I2096) (CBMAB-I3266-YY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Apoptotic process Source: MGI
Heart looping Source: Ensembl
Intraciliary transport Source: GO_Central
Left/right pattern formation Source: Ensembl
Motile cilium assembly Source: Ensembl
Negative regulation of epithelial cell proliferation Source: Ensembl
Neural tube closure Source: Ensembl
Non-motile cilium assembly Source: GO_Central
Regulation of apoptotic process Source: MGI
Smoothened signaling pathway Source: Ensembl
A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD18 is an autosomal recessive form characterized by short stature, brachymesophalangy, pre- and postaxial polysyndactyly, and stocky femoral necks, as well as oral anomalies and dysmorphic facial features.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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