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Mouse Anti-IGLL1 Recombinant Antibody (CBYJL-064) (CBMAB-L0116-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Immunoglobulin Lambda Like Polypeptide 1 (IGLL1). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all IGLL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYJL-064
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Immunoglobulin Lambda Like Polypeptide 1
Introduction
IGLL1 is critical for B-cell development.
Entrez Gene ID
Human3543
Mouse16136
Rat100360919
UniProt ID
HumanP15814
MouseP20764
RatF1MAM7
Alternative Names
14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2
Function
Critical for B-cell development.
Biological Process
B cell receptor signaling pathway Source: GO_Central
Complement activation, classical pathway Source: GO_Central
Defense response to bacterium Source: GO_Central
Immune response Source: UniProtKB
Innate immune response Source: GO_Central
Phagocytosis, engulfment Source: GO_Central
Phagocytosis, recognition Source: GO_Central
Positive regulation of B cell activation Source: GO_Central
Cellular Location
Endoplasmic reticulum; Secreted. In pre-B cells, localizes predominantly to the endoplasmic reticulum.
Involvement in disease
Agammaglobulinemia 2, autosomal recessive (AGM2):
A primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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