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Mouse Anti-ISL2 Recombinant Antibody (51.4H9) (CBMAB-0234-CN)


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Summary

Host Animal
Mouse
Specificity
Chicken
Clone
51.4H9
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Specificity
Chicken
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ISL LIM homeobox 2
Introduction
This gene has 2 transcripts (splice variants), 91 orthologues, 16 paralogues and is a member of 1 Ensembl protein family. It enceodes a transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. The protein acts in conjunction with LIM-1, LIM-3 and ISL-1.
Entrez Gene ID
396382
UniProt ID
P53410
Alternative Names
ISLET-2
Function
Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.
Biological Process
AxonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of neuron differentiationIEA:Ensembl
Neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Neuron fate specificationManual Assertion Based On ExperimentIBA:GO_Central
Peripheral nervous system neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Retinal ganglion cell axon guidanceIEA:Ensembl
Spinal cord motor neuron cell fate specificationIEA:Ensembl
Visceral motor neuron differentiationIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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