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ISL2

ISL2 (ISL LIM Homeobox 2) is a Protein Coding gene. Among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is ISL1.

Full Name

ISL LIM homeobox 2

Function

Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.

Biological Process

AxonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of neuron differentiationIEA:Ensembl
Neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Neuron fate specificationManual Assertion Based On ExperimentIBA:GO_Central
Peripheral nervous system neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Retinal ganglion cell axon guidanceIEA:Ensembl
Spinal cord motor neuron cell fate specificationIEA:Ensembl
Visceral motor neuron differentiationIEA:Ensembl

Cellular Location

Nucleus

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Anti-ISL2 antibodies

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Rabbit Anti-ISL2 Recombinant Antibody (EG1693) (CBMAB-EN2023-LY)

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Target: ISL2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1693

Application*: WB: 1:500~1:1000 ELISA: 1:20000

Mouse Anti-ISL2 Recombinant Antibody (1D9) (CBMAB-A4569-LY)

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Target: ISL2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1D9

Application*: WB, E

Mouse Anti-ISL2 Recombinant Antibody (203C5a) (CBMAB-I0714-YY)

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Target: ISL2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 203C5a

Application*: DB, IC, IF, WB

Mouse Anti-ISL2 Recombinant Antibody (51.4H9) (CBMAB-0234-CN)

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Target: ISL2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Chicken

Clone: 51.4H9

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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