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ISL2

ISL2 (ISL LIM Homeobox 2) is a Protein Coding gene. Among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is ISL1.
Full Name
ISL LIM homeobox 2
Function
Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.
Biological Process
AxonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of neuron differentiationIEA:Ensembl
Neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Neuron fate specificationManual Assertion Based On ExperimentIBA:GO_Central
Peripheral nervous system neuron developmentManual Assertion Based On ExperimentTAS:BHF-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Retinal ganglion cell axon guidanceIEA:Ensembl
Spinal cord motor neuron cell fate specificationIEA:Ensembl
Visceral motor neuron differentiationIEA:Ensembl
Cellular Location
Nucleus

Anti-ISL2 antibodies

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Target: ISL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 203C5a
Application*: DB, IC, IF, WB
Target: ISL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1693
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Target: ISL2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1D9
Application*: WB, E
Target: ISL2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Chicken
Clone: 51.4H9
Application*: E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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