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Mouse Anti-ITGB4 Recombinant Antibody (UM-A9) (CBMAB-C0865-CN)

This product is a Mouse antibody that recognizes ITGB4. The antibody UM-A9 can be used for immunoassay techniques such as: ELISA.
Host Animal
Mouse
Application
ELISA
Immunogen
Human squamous cell carcinoma (UM-SCC1). Cellular Localization: Cell surface
Antibody Isotype
IgG2a, κ
Cross Reactivity
Human
Clone
UM-A9
Format
Liquid
Introduction
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Name
Integrin Subunit Beta 4
Entrez Gene ID
UniProt ID
Cat CBMAB-C0865-CN
Conjugates
Size
Price $
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